Assuming they were the attackers,i would say its better to just hold your ground than rush head on into engagement with Empire of The Hands forces
>You can bait the enemy fleet to split their forces/pull their fighter screen off,by sending a small ship(Lancer/Carrack) or a fighter squadron to get their attention and drag them away
>Micromanage TIE interceptors against bombers before they have chance to get in range
>Focus your fire on Dagon Niriz(Imperial Star Destroyer),Stent(Ascendancy-Class star destroyer),Voss Parck(Victory Star destroyer) consider them as "soft" targets
>ArĀ“alani might look scary on her Syndic-Class Star Destroyer,but you should consider her as low priority target due to the ships incredible durability
>Bring enough Lancers to screen off any fighters/bombers that get too close,because when the main force connects you dont want to have bombers flying around freely
>I personaly prefer ISDs to SSDs,bringing 2 to 3 SSDs is overkill and not nessecarily in a good way
>Position your fleet with enough space to maneuver. if the Empire of the hand is focusing fire on single destroyer maneuver it to the back of the fleet
(forcing hand to go all out and possibly over extending)
simple tips/common knowledge.
would post more useful info if i had chance to properly test fleet compositions against Empire of the hand,but sadly work takes fair share of my time
edit:tlmiller being spot on with VSD-IIs and ISD-IIs being the top choices against this faction.