In Sins there’s no feature to “unresearch” something, and in Ascendancy due to the drawbacks present in late game techs for the factions this inability is more pronounced. In addition, while researching mutually disabling tech is an option (before the latest patch I would do so as the Imperials often to keep good ship building speed while also getting the defensive upgrades that slow down ship production) with the regime change you can’t research a new regime due to being locked out of it by in game requirements.